非奈利酮
Finerenone (Synonyms: BAY 94-8862)
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基本信息
中文名称非奈利酮
英文名称 Finerenone (Synonyms: BAY 94-8862)
CAS号1050477-31-0
分子式C21H22N4O3
分子量378.60
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862) displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
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