| 中文名称 | 非奈利酮 |
|---|---|
| 英文名称 | Finerenone (Synonyms: BAY 94-8862) |
| CAS号 | 1050477-31-0 |
| 分子式 | C21H22N4O3 |
| 分子量 | 378.60 |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862) displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
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