| 中文名称 | 甲氨蝶呤二钠盐 |
|---|---|
| 英文名称 | Methotrexate Disodium salt (Synonyms: Methotrexate disodium;Amethopterin disodium; CL14377 disodium; WR19039 disodium) |
| CAS号 | 7413-34-5 |
| 分子式 | C20H20N8Na2O5 |
| 分子量 | 498.40 |
| 外观 | Light yellow to yellow powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
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