中文名称 | 1-丁基-N-(2,6-二甲基苯基)-哌啶-2-甲酰胺; 左布比卡因;左旋布比卡因 |
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英文名称 | Levobupivacaine Base (Synonyms: (S)-(-)-Bupivacaine) |
CAS号 | 27262-47-1 |
分子式 | C₁₈H₂₈N₂O |
分子量 | 288.43 |
外观 | Off white crystalline powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Levobupivacaine ((S)-(-)-Bupivacaine) is a long-acting amide local anesthetic. Levobupivacaine exerts anesthetic and analgesic effects by reversibly blocking neuronal sodium channels. Levobupivacaine can inhibit the transmission and conduction of impulses in cardiovascular and other tissues, and has certain cardiac and central nervous system toxicity. Levobupivacaine is metabolized in the body by cytochrome P450 (CYP450). Levobupivacaine can also induce ferroptosis in gastric cancer through the miR-489-3p/SLC7A11 signaling pathway.
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