雷帕霉素 | 西罗莫司
Rapamycin (Synonyms: Sirolimus; AY-22989; NSC-2260804)
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中文名称雷帕霉素 | 西罗莫司
英文名称 Rapamycin (Synonyms: Sirolimus; AY-22989; NSC-2260804)
CAS号53123-88-9
分子式C51H79NO13
分子量914.18
外观White to off-white powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
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