| 中文名称 | 雷帕霉素 | 西罗莫司 |
|---|---|
| 英文名称 | Rapamycin (Synonyms: Sirolimus; AY-22989; NSC-2260804) |
| CAS号 | 53123-88-9 |
| 分子式 | C51H79NO13 |
| 分子量 | 914.18 |
| 外观 | White to off-white powder |
| 储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Rapamycin is a specific mTOR inhibitor with IC50 of ~0.1 nM HEK293 cells.Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator and an immunosuppressant.
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