中文名称 | 尼洛替尼盐酸盐一水合物 | 尼罗替尼盐酸盐一水合物 |
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英文名称 | Nilotinib Hydrochloride Monohydrate;Nilotinib HCl Monohydrate |
CAS号 | 923288-90-8 |
分子式 | C28H25ClF3N7O2 |
分子量 | 584.00 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Nilotinib (AMN-107, Tasigna) hydrochloride monohydrate is a selective and orally bioavailable inhibitor of Bcr-Abl with IC50 < 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
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