吡非尼酮
Pirfenidone (AMR69)
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500 mg 1 g
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In-stock
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¥480.00
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In-stock
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¥680.00
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基本信息
中文名称吡非尼酮
英文名称 Pirfenidone (AMR69)
CAS号53179-13-8
分子式C12H11NO
分子量197.33
外观White to light yellow powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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产品详情

Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.

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