(1R,2R,3R,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-羟基-6-甲基庚-2-基)-7a-甲基八氢-4H-茚-4-亚基)亚乙基)-2-(3-羟基丙氧基)-4-亚甲基环己烷-1,3-二醇; 艾地骨化醇;艾尔骨化醇
Eldecalcitol (Synonyms: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3)
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中文名称(1R,2R,3R,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-羟基-6-甲基庚-2-基)-7a-甲基八氢-4H-茚-4-亚基)亚乙基)-2-(3-羟基丙氧基)-4-亚甲基环己烷-1,3-二醇; 艾地骨化醇;艾尔骨化醇
英文名称 Eldecalcitol (Synonyms: ED-71; 2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3)
CAS号104121-92-8
分子式C30H50O5
分子量490.72
MDLMFCD25977156
外观White to off-white powder
储存条件4°C, protect from light, stored under nitrogen
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Eldecalcitol (ED-71), an oral vitamin D3 analog, is renowned for its potent inhibition of bone resorption and significant increase in bone mineral density, making it a valuable asset in osteoporosis treatment. Additionally, it exhibits anti-tumor properties by inhibiting cell proliferation, migration, and inducing apoptosis through the suppression of GPx-1, positioning it as a potential agent in cancer research and therapy.

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(1R,2R,3R,Z)-5-(2-((1R,3aS,7aR,E)-1-((R)-6-羟基-6-甲基庚-2-基)-7a-甲基八氢-4H-茚-4-亚基)亚乙基)-2-(3-羟基丙氧基)-4-亚甲基环己烷-1,3-二醇; 艾地骨化醇;艾尔骨化醇