| 中文名称 | (1R,4S,5S,6S)-4-氨基-2-硫杂双环[3.1.0]己烷-4,6-二甲酸 2,2-二氧化物 |
|---|---|
| 英文名称 | LY404039 (Synonyms: pomaglumetad;LY2140023) |
| CAS号 | 635318-11-5 |
| 分子式 | C₇H₉NO₆S |
| 分子量 | 235.21 |
| 外观 | White to gray powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
LY404039 is a potent, selective and orally active mGluR2 and mGluR3 agonist with Kis of 149 nM and 92 nM for recombinant human mGluR2 and mGluR3, respectively. LY404039 shows >100-fold selectivity for mGluR2/3 over other receptors/transproters. LY404039 has antipsychotic and anxiolytic effects.
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