草酸艾司西酞普兰/(S)-西酞普兰草酸盐
Escitalopram oxalate
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基本信息
中文名称草酸艾司西酞普兰/(S)-西酞普兰草酸盐
英文名称 Escitalopram oxalate
CAS号219861-08-2
分子式C20H21FN2O·C2H2O4
分子量414.43 | 324.40 (free)
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Escitalopram Oxalate (Cipralex; Lexapro; Lu10171; Lu-10171; Citalopram;Cytalopram), the oxalate salt of Escitalopram which is an approved antidepressant drug, is a potent and selective serotonin (5-HT) reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram Oxalate is the citalopram S-(+)-enantiomer. It has the ability to block [3H]-5-HT uptake and [125I]-RTI-55 binding in COS-1 cells that express the 5-HTT human serotonin transporter, with Ki values of 3.9±2.2nM and 6.6±1.4nM, respectively.

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