中文名称 | 草酸艾司西酞普兰/(S)-西酞普兰草酸盐 |
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英文名称 | Escitalopram oxalate |
CAS号 | 219861-08-2 |
分子式 | C20H21FN2O·C2H2O4 |
分子量 | 414.43 | 324.40 (free) |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Escitalopram Oxalate (Cipralex; Lexapro; Lu10171; Lu-10171; Citalopram;Cytalopram), the oxalate salt of Escitalopram which is an approved antidepressant drug, is a potent and selective serotonin (5-HT) reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram Oxalate is the citalopram S-(+)-enantiomer. It has the ability to block [3H]-5-HT uptake and [125I]-RTI-55 binding in COS-1 cells that express the 5-HTT human serotonin transporter, with Ki values of 3.9±2.2nM and 6.6±1.4nM, respectively.
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