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D-异亮氨酸

D-Isoleucine (Synonyms: (R)-Isoleucine)

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产品编号：CL2442

CAS No.：319-78-8

MDLNo：

分子式：C6H13NO2

分子量：131.17

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￥466.00

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基本信息

中文名称	D-异亮氨酸
英文名称	D-Isoleucine (Synonyms: (R)-Isoleucine)
CAS号	319-78-8
分子式	C6H13NO2
分子量	131.17
外观	White to off-white powder
储存条件	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

安全信息

产品详情

D-Isoleucine ((R)-Isoleucine), an isoleucine stereoisomer, is a selective activator of Asc-1 antiporter and can enhance hippocampal CA1-CA3 metabolism by releasing endogenous D-serine. Long term synergistic effect.
D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value.

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