中文名称 | PEAQX | NVP-AAM077 |
---|---|
英文名称 | PEAQX | NVP-AAM077 |
CAS号 | 459836-30-7 |
分子式 | C17H17BrN3O5P |
分子量 | 454.21 |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
PEAQX (NVP-AAM077) is an orally active and selective NMDA antagonist, with IC50 values of 270 nM and 29.6 μM for hNMDAR 1A/2A and hNMDAR 1A/2B, respectively. PEAQX can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures.
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