中文名称 | (R)-3-(1-(2,6-二氯-3-氟苯基)乙氧基)-5-(1-(哌啶-4-基)-1H-吡唑-4-基)吡啶-2-胺;克唑替尼 |
---|---|
英文名称 | Crizotinib (PF-02341066) |
CAS号 | 877399-52-5 |
分子式 | C21H22Cl2FN5O |
分子量 | 450.34 |
MDL | MFCD12407409 |
外观 | White to light brown powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Crizotinib (PF-02341066) is a potent, orally bioavailable small molecule inhibitor of c-Met and ALK that is bioavailable when taken orally. In assays based on cells, it inhibits c-Met and ALK with IC50 values of 11 nM and 24 nM, respectively.
© 2020-2024 凯立德生物医药技术(上海)有限公司 版权所有
沪ICP备15046197号-3
沪公网安备31011502007856号
Designed by Kuanersoft