2-((8-氯二苯并[b,f]硫杂卓-10-基)氧基)-N,N-二甲基乙胺
2-((8-Chlorodibenzo[b,f]thiepin-10-yl)oxy)-N,N-dimethylethan-1-amine; Zotepine
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中文名称2-((8-氯二苯并[b,f]硫杂卓-10-基)氧基)-N,N-二甲基乙胺
英文名称 2-((8-Chlorodibenzo[b,f]thiepin-10-yl)oxy)-N,N-dimethylethan-1-amine; Zotepine
CAS号26615-21-4
分子式C18H18ClNOS
分子量331.86
外观White to off-white powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM and 8 nM, respectively. Zotepine exhibits antidepressive and anxiolytic effects in vivo.


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