中文名称 | 立他司特 |
---|---|
英文名称 | Lifitegrast; SAR 1118 |
CAS号 | 1025967-78-5 |
分子式 | C29H24Cl2N2O7S |
分子量 | 615.48 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Lifitegrast, also known as SAR-1118, is an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Lifitegrast inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), thus lessening overall inflammatory responses.
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