Lisaftoclax (APG-2575; Bcl-2/Bcl-xl inhibitor 1)
(S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3-nitrophenyl)sulfonyl)-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4-chlorophenyl)spiro[3.5]non-6-en-7-yl)methyl)piperazin-1-yl)benzamide
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1 mg 5 mg
产品库存
3-5days
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¥2500.00
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产品库存
3-5days
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¥6500.00
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基本信息
中文名称Lisaftoclax (APG-2575; Bcl-2/Bcl-xl inhibitor 1)
英文名称 (S)-N-((4-(((1,4-dioxan-2-yl)methyl)amino)-3-nitrophenyl)sulfonyl)-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((6-(4-chlorophenyl)spiro[3.5]non-6-en-7-yl)methyl)piperazin-1-yl)benzamide
CAS号2180923-05-9
分子式C45H48ClN7O8S
分子量882.42
外观Light yellow to yellow powder
储存条件 Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1; APG2575) is a novel and potent dual inhibitor of Bcl-2 and Bcl-xl with anticancer activity. It inhibits Bcl-2 and Bcl-xl with IC50 of 2 nM and 5.9 nM, respectively.

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Lisaftoclax (APG-2575; Bcl-2/Bcl-xl inhibitor 1)