中文名称 | 赛乐西帕 | 司来帕格 |
---|---|
英文名称 | NS-304 (Selexipag; ACT-293987) |
CAS号 | 475086-01-2 |
分子式 | C26H32N4O4S |
分子量 | 496.62 |
外观 | White to yellow powder |
Selexipag, also known as ACT-293987 and NS-304, is a a first-in-class orally available selective non-prostanoid IP receptor agonist, which is currently in development by Actelion as a treatment of pulmonary arterial hypertension. Selexipag and its active metabolite, ACT-333679, are agonists at the prostacyclin receptor, which leads to vasodilation in the pulmonary circulation.
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