马来酸茚达特罗 | 茚达特罗马来酸盐
Indacaterol Maleate (Synonyms: QAB149)
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产品库存
3-5days
目录价格
¥850.00
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产品库存
3-5days
目录价格
¥1360.00
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产品库存
3-5days
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¥2300.00
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基本信息
中文名称马来酸茚达特罗 | 茚达特罗马来酸盐
英文名称 Indacaterol Maleate (Synonyms: QAB149)
CAS号753498-25-8
分子式C28H32N2O7
分子量508.56
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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产品详情

Indacaterol Maleate (formerly known as QAB149; QAB-149; Onbrez Breezhale; arcapta neohaler; Onbrez), the maleate salt of indacaterol, is an approved anti-COPD (chronic obstructive pulmonary disease) drug acting as an ultra-long-acting β-adrenoceptor agonist developed by Novartis. β-adrenoceptor is activated with a pKi of 7.36 in. The FDA approved indacaterol in 2009 to treat chronic obstructive pulmonary disease (COPD). Using a dry powder inhaler, the aerosol formulation is administered. When Chinese hamster ovary cells are transfected with human β2 adrenoceptors and have a pEC50 of 8.06, indacaterol inhibits the production of cAMP.
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