中文名称 | 恩曲他滨 |
---|---|
英文名称 | Emtricitabine (BW1592) |
CAS号 | 143491-57-0 |
分子式 | C8H10FN3O3S |
分子量 | 247.25 |
外观 | White to off-white powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Emtricitabine (BW1592; FTC; Coviracil; Emtriva; Racivir) is a potent nucleoside reverse transcriptase inhibitor (NRTI) with an EC50 of 0.01 µM and has been used for the treatment of both human immunodeficiency virus (HIV) and hepatitis B virus. Emtricitabine is structurally similar to Lamivudine. It is effective at targeting HIV and HBV viruses since these viruses replicate in a reverse transcriptase manner. Studies indicate that the structure of Emtricitabine, specifically the unnatural β-L structural configuration produce greater antiviral effects in vitro on HIV and HBV than other antiviral agents. nucleoside reverse transcriptase inhibitor.
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