中文名称 | ALM301 |
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英文名称 | ALM301 |
CAS号 | 1313439-71-2 |
分子式 | C25H25N3O3 |
分子量 | 415.48 |
外观 | Off-white to light yellow |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
ALM301 is an orally bioactive, specific AKT inhibitor (antagonist) with IC50s of 0.13 μM, 0.09 μM, and 2.75 μM for AKT1, AKT2, and AKT3, respectively. ALM301 inhibits AKT phosphorylation and regulates downstream signaling in vitro. ALM301 inhibits cancer/tumor cell growth/proliferation and tumor
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