克拉生坦
Clazosentan
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基本信息
中文名称克拉生坦
英文名称 Clazosentan
CAS号180384-56-9
分子式C25H23N9O6S
分子量577.57
外观Off-white to light yellow powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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Clazosenta (Ro 61-1790, VML-588 and AXV-034) is a novel and highly potent endothelin A antagonist which improves cerebral blood flow and behavior after traumatic brain injury. Clazosentan is being developed in clinical trials for the treatment of patients with aneurysmal subarachnoid hemorrhage (SAH) by Actelion Pharmaceuticals.Clazosentant decreases and reverses cerebral vasospasm after experimental SAH. Clazosentanthas been shown to reduce vasospasm after aneurysmal subarachnoid hemorrhage (aSAH).

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