PXL770
PXL770
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基本信息
中文名称PXL770
英文名称 PXL770
CAS号1523493-53-9
分子式C23H18ClNO3S
分子量423.91
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation. PXL770 can be used in the study of non-alcoholic fatty liver disease (NAFLD).

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