中文名称 | BIX-01294盐酸盐水合物 |
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英文名称 | BIX-01294 hydrochloride hydrate |
CAS号 | 1808255-64-2 |
分子式 | C28H38N6O2.3ClH.xH2O |
分子量 | |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
BIX-01294 hydrochloride hydrate is a histone-lysine methyltransferase (HMTase) inhibitor, which selective inhibits the G9aHMTase with IC50 of 1.7 μM, reduces histone-3 lysine (9) methylation (H3K9me), induces autophagy and apoptosis in human glioma cells.
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