T0070907
T0070907
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基本信息
中文名称T0070907
英文名称 T0070907
CAS号313516-66-4
分子式C12H8ClN3O3
分子量277.66
外观White to light yellow powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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T0070907 is a potent inhibitor of PPARγ (peroxisome proliferator activator receptor γ ) that induces G2/M arrest and enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. It also acts as an antagonist of PPARγ that suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms.T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.
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