中文名称 | (Z)-奥兰替尼 | (Z)-SU6668 | (Z)-TSU-68 |
---|---|
英文名称 | (Z)-Orantinib | (Z)-SU6668 | (Z)-TSU-68 |
CAS号 | 210644-62-5 |
分子式 | C18H18N2O3 |
分子量 | 310.35 |
外观 | Orange to red powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
(Z)-Orantinib ((Z)-SU6668) is a potent, selective, orally active and ATP competitive inhibitor of Flk‐1/KDR, PDGFRβ, and FGFR1, with IC 50 s of 2.1, 0.008, and 1.2 μM, respectively. (Z)-Orantinib is a potent antiangiogenic and antitumor agent that induces established tumor regression.
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