中文名称 | (3S,4S)-替万替尼 |
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英文名称 | (3S,4S)-Tivantinib | 3S,4S)-ARQ 197 | ARQ 198 |
CAS号 | 905854-03-7 |
分子式 | C23H19N3O2 |
分子量 | 369.42 |
外观 | Off-white to light yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
(3S,4S)-Tivantinib is a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET. (3S,4S)-Tivantinib has two novel targets, GSK3α and GSK3β, which play an important role in the cellular mechanism of non-small cell lung cancer (NSCLC).
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