中文名称 | 他立喹达二甲磺酸盐 |
---|---|
英文名称 | Tariquidar dimesylate | XR9576 dimesylate |
CAS号 | 625375-84-0 |
分子式 | C38H38N4O6 · 2 CH4O3S |
分子量 | 838.94 | 646.74 (free) |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Tariquidar dimesylate (XR9576 dimesylate) is a P-glycoprotein (P-gp) inhibitor. Tariquidar dimesylate increases the concentration of the drug in the brain by binding to P-glycoprotein, preventing it from transporting the drug from inside to outside the brain. Tariquidar dimesylate can be used in the study of blood-brain barrier penetration and multidrug resistance.
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