中文名称 | PF-477736 | PF-736 | PF-00477736 |
---|---|
英文名称 | PF-477736 | PF-736 | PF-00477736 |
CAS号 | 952021-60-2 |
分子式 | C22H25N7O2 |
分子量 | 419.48 |
PF-477736 (PF-736, PF-00477736) is a selective, potent and ATP-competitive Chk1 inhibitor with Ki of 0.49 nM in a cell-free assay and also inhibits VEGFR2, Aurora-A, FGFR3, Flt3, Fms (CSF1R), Ret and Yes. It shows ~100-fold selectivity for Chk1 than Chk2.
© 2020-2024 凯立德生物医药技术(上海)有限公司 版权所有
沪ICP备15046197号-3
沪公网安备31011502007856号
Designed by Kuanersoft