替罗非班 | L700462 | MK383
Tirofiban (Synonyms: L700462; MK383)
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基本信息
中文名称替罗非班 | L700462 | MK383
英文名称 Tirofiban (Synonyms: L700462; MK383)
CAS号144494-65-5
分子式C22H36N2O5S
分子量440.60
外观White to off-white powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
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Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.


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替罗非班 | L700462 | MK383