中文名称 | 盐酸替罗非班 | 盐酸替洛非巴 |
---|---|
英文名称 | Tirofiban hydrochloride | L700462 hydrochloride | MK383 hydrochloride) |
CAS号 | 142373-60-2 |
分子式 | C22H37ClN2O5S |
分子量 | 477.06 |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Tirofiban (L700462) hydrochloride is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
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