中文名称 | YKL-05-099 |
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英文名称 | YKL-05-099 |
CAS号 | 1936529-65-5 |
分子式 | C32H34ClN7O3 |
分子量 | 600.11 |
外观 | White to light yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
YKL-05-099 is a salt-inducible kinase (SIK) inhibitor. YKL-05-099 binds to SIK1 and SIK3 with IC50s of ~10 and ~30 nM, respectively. YKL-05-099 has slightly less potent SIK2-inhibitory (IC50=40 nM).
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