中文名称 | 盐酸罗格列酮 |
---|---|
英文名称 | Rosiglitazone HCl | BRL 49653 hydrochloride |
CAS号 | 302543-62-0 |
分子式 | C18H19N3O3S·HCl |
分子量 | 393.89 | 357.43 (free) |
外观 | White to off-white powder |
储存条件 | -20°C, sealed storage, away from moisture |
Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer.
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