中文名称 | 罗格列酮 |
---|---|
英文名称 | Rosiglitazone | BRL 49653 |
CAS号 | 122320-73-4 |
分子式 | C18 H19N3O3S |
分子量 | 357.43 |
外观 | White to off-white powder |
储存条件 | 4°C, 2 years | -20°C,3 years |
Rosiglitazone (BRL 49653) is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone is an TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone can be used in the research of obesity and diabetes, senescence, ovarian cancer.
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