中文名称 | R547 | Ro 4584820 |
---|---|
英文名称 | R547 | Ro 4584820 |
CAS号 | 741713-40-6 |
分子式 | C18H21F2N5O4S |
分子量 | 441.45 |
外观 | White to off-white powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases.
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