中文名称 | 盐酸罗哌卡因 |
---|---|
英文名称 | Ropivacaine hydrochloride |
CAS号 | 98717-15-8 |
分子式 | C17H26N2O·HCl |
分子量 | 310.86 | 274.41(free) |
外观 | White to off-white powder |
储存条件 | 4°C, sealed storage, away from moisture |
Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is widely used for neuropathic pain management in vivo.
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