| 中文名称 | 罗哌卡因 |
|---|---|
| 英文名称 | Ropivacaine |
| CAS号 | 84057-95-4 |
| 分子式 | C17H26N2O |
| 分子量 | 274.40 |
| 外观 | White to off-white powder |
| 储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is used for the research of neuropathic pain management.
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