中文名称 | 甲磺酸罗哌卡因 |
---|---|
英文名称 | Ropivacaine mesylate |
CAS号 | 854056-07-8 |
分子式 | C17H26N2O·CH4O3S |
分子量 | 370.51 | 274.41 |
外观 | White to off-white powder |
储存条件 | 4°C, sealed storage, away from moisture |
Ropivacaine mesylate is a long-acting amide local anaesthetic agent for a spinal block and effectively blocks neuropathic pain. Ropivacaine blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane.
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