中文名称 | Gandotinib | LY2784544 |
---|---|
英文名称 | Gandotinib | LY2784544 |
CAS号 | 1229236-86-5 |
分子式 | C23H25ClFN7O |
分子量 | 469.94 |
外观 | Light yellow to yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3.
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