中文名称 | SKLB4771 | FLT3-IN-1 |
---|---|
英文名称 | SKLB4771 | FLT3-IN-1 |
CAS号 | 1370256-78-2 |
分子式 | C25H27N7O3S2 |
分子量 | 537.66 |
外观 | Light yellow to yellow powder |
储存条件 | Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃. |
SKLB4771 is a potent and selective Flt3 inhibitor with an IC50 value of 10 nM. SKLB4771 downregulates the phosphorylation of FLT3/STAT5/ERK, blocks cell proliferation, and induces apoptosis in tumor tissue.
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