中文名称 | 鲁索替尼硫酸盐 | 鲁索利替尼硫酸盐 |
---|---|
英文名称 | Ruxolitinib sulfate | INCB018424 sulfate |
CAS号 | 1092939-16-6 |
分子式 | C17H18N6 · H2SO4 |
分子量 | 404.44 | 306.37(free) |
外观 | Off-white to gray powder |
储存条件 | 4°C, sealed storage, away from moisture |
Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.
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