SR-4835
SR-4835
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5 mg 10 mg
产品库存
3-5days
目录价格
¥468.00
会员价格
产品库存
3-5days
目录价格
¥798.00
会员价格
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基本信息
中文名称SR-4835
英文名称 SR-4835
CAS号2387704-62-1
分子式C21H20Cl2N10O
分子量499.36
外观Off-white to light brown powder
储存条件Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
安全信息
产品详情

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.


相关文献
PMID: 31668947 DOI: 10.1016/j.ccell.2019.09.004
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SR-4835