中文名称 | LY2780301 |
---|---|
英文名称 | LY2780301 |
CAS号 | 1226801-23-5 |
分子式 | C25H27F4N7O |
分子量 | 517.52 |
LY2780301 is a highly selective adenosine triphosphate (ATP)-competitive dual inhibitor of p70S6K and Akt. LY2780301 binds to Akt, inhibiting its activity, which consequently blocks the PI3K/Akt signaling pathway which leads to reduced cell proliferation and the initiation of apoptosis in tumor cells.
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