中文名称 | MK-2894 |
---|---|
英文名称 | MK-2894 |
CAS号 | 1006036-87-8 |
分子式 | C25H22F3NO3S |
分子量 | 473.51 |
外观 | White to light brown powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
MK-2894 is a potent, selective, orally active and high affinity (Ki=0.56 nM) full antagonist against E prostanoid receptor 4 (EP4 receptor) (IC50=2.5 nM). MK-2894 possesses potent anti-inflammatory activity in animal models of pain/inflammation and can be used for the research of arthritis.
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