| 中文名称 | 白僵菌素 | 白僵菌毒素 |
|---|---|
| 英文名称 | Beauvericin |
| CAS号 | 26048-05-5 |
| 分子式 | C45H57N3O9 |
| 分子量 | 783.95 |
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis, thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages.
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