中文名称 | 氟达拉滨 | 氟达拉滨碱 |
---|---|
英文名称 | Fludarabine | Fara A | Fludarabinum | Fludarabine | F-ara-A | NSC 118218 Base |
CAS号 | 21679-14-1 |
分子式 | C10H12FN5O4 |
分子量 | 285.23 |
外观 | White to yellow powder |
储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Fludarabine (NSC 118218) is a DNA synthesis inhibitor and a fluorinated purine analogue with antineoplastic activity in lymphoproliferative malignancies. Fludarabine inhibits the cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in normal resting or activated lymphocytes.
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