中文名称 | 4-氨基-1-((2S,4S)-2-(羟甲基)-1,3-二氧杂戊环-4-基)嘧啶-2(1H)-酮; 曲沙他滨 |
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英文名称 | Troxacitabine (Synonyms: BCH 4556; L-OddC; SPD 758) |
CAS号 | 145918-75-8 |
分子式 | C8H11N3O4 |
分子量 | 213.19 |
MDL | MFCD00871100 |
外观 | White to off-white powder |
储存条件 | 4°C, protect from light |
Troxacitabine, a DNA polymerase inhibitor, shows potential in treating acute myeloid leukemia (AML) and has demonstrated activity against pancreatic cancer cell lines MiaPaCa and Panc-01, with greater efficacy against Panc-01. As a nucleoside analog, it possesses significant anticancer properties.
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