| 中文名称 | 5-碘代杀结核菌素 |
|---|---|
| 英文名称 | 5-Iodotubercidin (Synonyms: NSC 113939; 5-ITu) |
| CAS号 | 24386-93-4 |
| 分子式 | C11H13IN4O4 |
| 分子量 | 392.15 |
5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin.
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