GDC-0879
GDC-0879
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基本信息
中文名称GDC-0879
英文名称 GDC-0879
CAS号905281-76-7
分子式C19H18N4O2
分子量334.37
外观White to light brown powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
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GDC-0879 is a highly selective, potent, and orally bioavailable RAF small-molecule inhibitor. In GDC-0879 -treated mice, both cell line- and patient-derived BRAF(V600E) tumors exhibited stronger and more sustained pharmacodynamic inhibition (>90% for 8 hours) and improved survival compared with mutant KRAS-expressing tumors.


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GDC-0879
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