中文名称 | 8-(4-(1-氨基环丁基)苯基)-9-苯基-[1,2,4]三唑并[3,4-f][1,6]萘啶-3(2H)-酮二盐酸盐 |
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英文名称 | MK-2206 dihydrochloride | MK-2206 ·2HCl |
CAS号 | 1032350-13-2 |
分子式 | C25H23N5O· 2HCl |
分子量 | 482.40 |
MDL | MFCD14584463 |
外观 | Yellow powder |
储存条件 | 4°C, sealed storage, away from moisture |
MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active, BBB-penetrated allosteric AKT inhibitor with IC50s of 5 nM, 12 nM, and 65 nM for AKT1, AKT2, and AKT3, respectively. MK-2206 dihydrochloride induces autophagy.
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