中文名称 | 2-(5-((7-(3-(乙基(2-羟乙基)氨基)丙氧基)喹唑啉-4-基)氨基)-1H-吡唑-3-基)-N-(3-氟苯基)乙酰胺;巴拉塞替-HQPA |
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英文名称 | Barasertib-HQPA (Synonyms: AZD2811; INH-34; AZD1152-HQPA) |
CAS号 | 722544-51-6 |
分子式 | C26H30FN7O3 |
分子量 | 507.56 |
MDL | MFCD17392583 |
外观 | White to yellow powder |
储存条件 | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
Barasertib-HQPA (AZD2811) is a highly selective Aurora kinase B inhibitor with an IC50 value of 0.37 nM in cell-free assays. Barasertib-HQPA (AZD2811) has the potential to induce growth arrest and apoptosis in cancer cells.
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