N-(7,8-二甲氧基-2,3-二氢咪唑并[1,2-c]喹唑啉-5-基)烟酰胺
PIK-90
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基本信息
中文名称N-(7,8-二甲氧基-2,3-二氢咪唑并[1,2-c]喹唑啉-5-基)烟酰胺
英文名称 PIK-90
CAS号677338-12-4
分子式C18H17N5O3
分子量351.36
MDLMFCD12910483
外观Off-white to yellow powder
储存条件Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.
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PIK-90 is recognized as a potent inhibitor of both DNA-PK and PI3K, demonstrating its inhibitory effects on the p110α, p110γ, and DNA-PK with respective IC50 values of 11, 18, and 13 nM. This compound plays a significant role in the realm of molecular biology and cancer research, where its ability to target these key enzymes is of paramount importance. 

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N-(7,8-二甲氧基-2,3-二氢咪唑并[1,2-c]喹唑啉-5-基)烟酰胺