中文名称 | N-(7,8-二甲氧基-2,3-二氢咪唑并[1,2-c]喹唑啉-5-基)烟酰胺 |
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英文名称 | PIK-90 |
CAS号 | 677338-12-4 |
分子式 | C18H17N5O3 |
分子量 | 351.36 |
MDL | MFCD12910483 |
外观 | Off-white to yellow powder |
储存条件 | Store short-term at 0-4°C or long-term at -20°C in a dry, dark place. |
PIK-90 is recognized as a potent inhibitor of both DNA-PK and PI3K, demonstrating its inhibitory effects on the p110α, p110γ, and DNA-PK with respective IC50 values of 11, 18, and 13 nM. This compound plays a significant role in the realm of molecular biology and cancer research, where its ability to target these key enzymes is of paramount importance.
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